This Sleep Pattern Accelerates Memory Loss – Possible Link to Alzheimer’s

Sleep pattern lowered levels of an antioxidant that helps fight cellular damage, such as that caused by Alzheimer’s.

Sleep pattern lowered levels of an antioxidant that helps fight cellular damage, such as that caused by Alzheimer’s.

Sleep disruptions similar to jet lag could cause memory problems linked to Alzheimer’s disease, research finds.

It’s well-known by scientists that there’s a link between Alzheimer’s and sleep, but not what causes what.

Professor Gregory Brewer, who led the research, said:

“The issue is whether poor sleep accelerates the development of Alzheimer’s disease or vice versa.

It’s a chicken-or-egg dilemma, but our research points to disruption of sleep as the accelerator of memory loss.”

The research gave jet-lag to mice that had been genetically engineered to suffer from Alzheimer’s.

They did this by moving the dark period every three days to a different time — which is what causes jet-lag.

The jet-lagged mice had lower levels of an antioxidant that helps fight cellular damage, such as that caused by Alzheimer’s.

This suggests it could be poor sleep that is contributing to the risk of developing Alzheimer’s disease.

Professor Brewer said:

“This study suggests that clinicians and caregivers should add good sleep habits to regular exercise and a healthy diet to maximize good memory.”

Dementia and sleep

Many other studies have found a link between dementia and sleep.

People who sleep for too little or too long are at a higher risk of cognitive decline and dementia.

Indeed, people who sleep more than 9 hours a night have double the risk of developing dementia, one study found.

However, those who sleep for between 5.5 and 7.5 hours per night do not see declines in their cognitive health, even when suffering the early effects of Alzheimer’s disease.

Those sleeping longer also have lower brain volumes.

Also, getting less REM sleep — the phase in which we dream — is linked to dementia.

During sleep the brain cycles between periods of deep sleep and then up towards shallower periods of sleep in which we tend to dream, whether we remember those dreams or not.

During REM sleep the eyes move rapidly from side-to-side (hence Rapid Eye Movement Sleep).

Sleep apnea has also been linked to developing Alzheimer’s disease.

The most common signs of sleep apnea, which affects 30 percent of older people, include:

  • Loud snoring,
  • gasping for air during sleep,
  • breathing stopping for brief periods during the night,
  • morning headache,
  • and daytime sleepiness and irritability.

The study was published in the Journal of Alzheimer’s Disease (Brewer et al., 2015).

A Simple Trick To Help You Remember Anything

Memory is dynamic, but it needs this clue as to what it should store away so you remember more.

Memory is dynamic, but it needs this clue as to what it should store away so you remember more.

Telling someone else a piece of information helps lodges it into your own memory more securely, psychological research finds.

People in the study who immediately told others a piece of information could remember more later and they remembered it for longer.

Dr Melanie Sekeres, the study’s lead author, explained:

“This has to be actively replaying or re-generating the information — for example, by telling someone the particulars, as opposed to just simply re-reading the textbook or class notes and studying it again later.

A week later, the memory was just as good.

Telling someone else about what you’ve learned is a really effective way for students to study instead of just re-reading the textbook or class notes.”

For the study students were trying to remember the general plots of films and certain details in the films.

Small cues — like the title of the film — were also enough to help students recall the film’s details.

Dr Sekeres said:

“With a cue, suddenly, a lot of those details will come back.

We don’t permanently forget them, which would indicate lack of storage — we just can’t immediately access them.

And that’s good.

That means our memories aren’t as bad as we think.”

Dr Sekeres explained the nature of the films used in the study:

“We chose mostly foreign films and somewhat obscure clips that we thought most undergraduates would not have seen.

The clips all contained brief scenes of normal, everyday events that mimicked the kind of events you might experience in a day, such as a family having dinner or kids playing at a park.”

How to remember more

Trying to explain the information to someone else can be tiring, but the effort is worth it:

“We tell students to test yourself, force yourself to tell someone about the lecture.

Even by writing out some questions for yourself about the information, then later answering them yourself, you are more likely to remember the information.

Unfortunately, simply re-reading or passively listening to a recording of your lecture in the hopes of remembering the information isn’t a great study strategy by comparison.”

The reason testing and re-testing works is because the brain is adaptive:

“We remember the important things, for the most part, and we forget the unimportant details.

You don’t want your brain to search through tons of useless information.”

The study was published in the journal Learning & Memory (Sekeres et al., 2016).

6 Foods That Protect Against Memory Loss

The foods all contain an anti-inflammatory that combats age-related changes in the brain.

The foods all contain an anti-inflammatory that combats age-related changes in the brain.

Carrots, olive oil, celery, thyme, peppermint and chamomile can all help protect the memory against aging, research suggests.

All these foods contain luteolin, a flavonoid which is found in many plants.

Luteolin reduces inflammation in the brain that occurs with aging.

It does so by inhibiting the release of inflammatory molecules in the brain.

The conclusions come from a study of mice, Professor Rodney Johnson, who led the study, explained:

“When we provided the old mice luteolin in the diet it reduced inflammation in the brain and at the same time restored working memory to what was seen in young cohorts.”

Working memory is vital to holding pieces of visual, verbal or other information in your mind while you manipulate them.

Better working memory has been linked to improved learning, attention and other vital outcomes.

Professor Johnson continued:

“We believe dietary luteolin accesses the brain and inhibits or reduces activation of microglial cells and the inflammatory cytokines they produce.

This anti-inflammatory effect is likely the mechanism which allows their working memory to be restored to what it was at an earlier age.

These data suggest that consuming a healthy diet has the potential to reduce age-associated inflammation in the brain, which can result in better cognitive health.”

Other common sources of luteolin include broccoli, green pepper, oregano and parsley.

Luteolin works, the study found, by acting directly on microglial cells.

The microglia are cells in the brain that help regulate normal functioning.

Professor Johnson said:

“We found previously that during normal aging, microglial cells become dysregulated and begin producing excessive levels of inflammatory cytokines.

We think this contributes to cognitive aging and is a predisposing factor for the development of neurodegenerative diseases.”

For the study, younger and older mice were fed a control diet or one supplemented with luteolin for four weeks.

The results showed that older mice given the luteolin supplement performed almost as well as the younger mice in cognitive tests.

The study was published in the Journal of Nutrition (Jang et al., 2010).

How Nature Reshapes Your Perception Of Time And Memory (M)

Learn how reminiscing about the past differs in urban and natural settings, and why it matters for your mental health.

Learn how reminiscing about the past differs in urban and natural settings, and why it matters for your mental health.


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The #1 Cause Of Memory Loss And 3 Proven Ways To Avoid It

The advice comes from a study of chronic inflammation in the body.

The advice comes from a study of chronic inflammation in the body.

The number one cause of memory loss is simply aging.

A little forgetfulness is normal and does not necessarily indicate a problem.

However, there are ways to fight against this natural process and retain a better memory.

The three best ways to avoid memory loss later in life are:

  1. Eating an anti-inflammatory heart-healthy diet,
  2. getting enough sleep,
  3. and exercising regularly.

The advice comes from a study of chronic inflammation in the body.

Inflammation in middle age is linked to memory and thinking problems later on, research shows.

The main problem is chronic inflammation that continues for months or even years.

Symptoms of chronic inflammation include joint pain and stiffness, digestive problems and fatigue.

Dr  Keenan A. Walker, the study’s first author, said:

“Many of the processes that can lead to a decline in thinking and memory skills are believed to begin in middle age, and it is in middle age that they may also be most responsive to intervention.

Our results show that chronic inflammation may be an important target for intervention.

However, it’s also possible that chronic inflammation is not a cause and instead a marker of, or even a response to, neurodegenerative brain diseases that can lead to cognitive decline.”

The study followed 12,336 people for an average of 20 years.

All were given blood tests for inflammation markers.

The results showed that people with the highest levels of inflammation also had the worst thinking and memory skills.

Those with the highest levels of inflammation had 8 percent worse scores on cognitive tests than those with the lowest levels.

Dr  Walker continued:

“Chronic inflammation is tough on the body, and can damage joints, internal organs, tissue and cells.

It can also lead to heart disease, stroke and cancer.

While other studies have looked at chronic inflammation and its effects on the brain in older people, our large study investigated chronic inflammation beginning in middle age and showed that it may contribute to cognitive decline in the decades leading up to old age.”

The study was published in the journal Neurology (Walker et al., 2019).

2 Easy Ways To Make Memories That Lasts A Lifetime

Why some memories last a lifetime and others are quickly forgotten.

Why some memories last a lifetime and others are quickly forgotten.

Memories that last a lifetime need to be linked to lots of other memories, plus they need to be a bit weird.

These are the two key components of memories that have the potential to last a lifetime.

Professor Per Sederberg, an expert on memory, thinks the idea of peculiarity is vital to understanding memory:

“You have to build a memory on the scaffolding of what you already know, but then you have to violate the expectations somewhat.

It has to be a little bit weird.”

This ‘scaffolding’ means connections to other memories.

For example, memories of our childhoods are linked to lots of other memories about our families and the places we lived.

And which are the stories we remember best — the ones that stand out?

Of course, it is the ones where something unusual happened: when Grandad told you he was in a band years ago and astonished you by playing the guitar.

It is when you were cycling home and happened to pass your mother in the street wearing a dragon costume and holding a cricket bat.

How memories are stored and retrieved

In one of Professor Sederberg’s studies people wore smartphones around their necks for a month.

These automatically took photos at random intervals.

Later, they relived these memories in the brain scanner so researchers could see where and how the memories were stored and retrieved.

Think of all your memories as being like a vast network, Professor Sederberg said:

“If we want to be able to retrieve a memory later, you want to build a rich web.

It should connect to other memories in multiple ways, so there are many ways for our mind to get back to it.

You want to have a lot of different ways to get to any individual memory.”

Memorable experiences often happen in familiar contexts, but have some peculiar, unpredictable aspect, said Professor Sederberg:

“Those peculiar experiences are the things that stand out, that make a more lasting memory.”

This is why some memories last a lifetime and others are quickly forgotten.

Professor Sederberg was speaking at the Cannes Lions Festival of Creativity in France on June 19. The study referenced was published in the journal PNAS (Nielson et al., 2015).

This Supplement Improves Memory – Even Of Healthy Young People

Working memory is vital to holding pieces of visual, verbal or other information in your mind while you manipulate them.

Working memory is vital to holding pieces of visual, verbal or other information in your mind while you manipulate them.

Even healthy young people can improve their memory by increasing their omega-3 intake, research finds.

The six-month study showed that omega-3 supplements increased people’s working memory.

Professor Bita Moghaddam, a study author, said:

“Before seeing this data, I would have said it was impossible to move young healthy individuals above their cognitive best.

We found that members of this population can enhance their working memory performance even further, despite their already being at the top of their cognitive game.”

Working memory is vital to holding pieces of visual, verbal or other information in your mind while you manipulate them.

Better working memory has been linked to improved learning, attention and other vital outcomes.

Dr Matthew Muldoon, a study co-author, said:

“So many of the previous studies have been done with the elderly or people with medical conditions, leaving this unique population of young adults unaddressed.

But what about our highest-functioning periods?

Can we help the brain achieve its full potential by adapting our healthy behaviors in our young adult life?

We found that we absolutely can.”

The team were also hoping to find the mechanism in the brain that was linked to the improvement in working memory.

Unfortunately brain scans did not reveal evidence of the mechanism they were looking for.

Dr Rajesh Narendarn, the study’s first author, said:

“It is really interesting that diets enriched with Omega-3 fatty acid can enhance cognition in highly functional young individuals.

Nevertheless, it was a bit disappointing that our imaging studies were unable to clarify the mechanisms by which it enhances working memory.”

Participants in the study took a supplement called Lovaza (essentially, fish oil or omega-3) at a dosage of 2g per day.

The supplement had roughly equal amounts of DHA and EPA.

The study was published in the journal PLoS ONE (Narendran et al., 2012).

These Sleep Patterns Are Linked To 50% Increased Dementia Risk & Memory Loss (M)

Are you sleeping right? How your sleep patterns might shape your cognitive destiny.

Are you sleeping right? How your sleep patterns might shape your cognitive destiny.


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