Category: Alcohol

New brain cells in the hippocampus — an area critical for memory — were reduced by 40%.

Even moderate alcohol intake could reduce the brain’s ability to produce new cells by 40 percent, research suggests.

Regularly having as little as 3 to 4 alcoholic drinks could reduce the structural integrity of the adult brain.

Ms Megan Anderson, the study’s first author, said:

“Moderate drinking can become binge drinking without the person realizing it.

In the short term there may not be any noticeable motor skills or overall functioning problems, but in the long term this type of behavior could have an adverse effect on learning and memory.”

The conclusions come from a rodent study in which the animals were given the equivalent amount of alcohol to reach the legal driving limit.

This amount of alcohol did not have much effect on their motor coordination.

However, the results showed that the production of new brain cells in the hippocampus — an area critical for memory — were reduced by 40%.

Ms Anderson said:

“…this substantial decrease in brain cell numbers over time could have profound effects on the structural plasticity of the adult brain because these new cells communicate with other neurons to regulate brain health.

If this area of your brain was affected every day over many months and years, eventually you might not be able to learn how to get somewhere new or to learn something new about your life.

It’s something that you might not even be aware is occurring.”

Drinker who are ‘at risk’ are currently defined as men who have 14 drinks per week or more and women who have 7 or more per week.

Ms Anderson said:

“This research indicates that social or daily drinking may be more harmful to brain health than what is now believed by the general public.”

The study was published in the journal Neuroscience (Anderson et al., 2012).

The more alcohol people drank, the greater the damage to the cerebral cortex.

High alcohol intake can lead to a thinner cerebral cortex, research finds.

The cerebral cortex is the layer of neurons that supports most higher-level cognition.

However, the brain damage caused by drinking is not an all-or-nothing phenomenon.

The more people drank, the greater the damage to this area of the brain.

The irony is that alcohol damages the very areas of the brain that are responsible for controlling alcohol intake.

However, people who had been alcoholics but now abstained showed the brain can recover.

Dr Catherine Brawn Fortier, the study’s first author, said:

“We now know that alcohol has wide ranging effects across the entire cortex and in structures of the brain that contribute to a wide range of psychological abilities and intellectual functions.”

Alcohol affects both the gray and white matter in the brain.

The greatest impact, though, is seen in the temporal lobes.

Dr Fortier explained:

“These brain areas are critical to learning new information and, even more importantly, in self-regulation, impulse control, and the modification of all complicated human behaviors.

In other words, the very parts of the brain that may be most important for controlling problem drinking are damaged by alcohol, and the more alcohol consumed, the greater the damage.”

How alcohol affects the cerebral cortex study

The conclusions come from brain scans of 65 people, some of whom were recovering alcoholics and others who were nonalcoholics.

Dr Fortier explained the study’s results:

“First, the outermost layer of cortex across the entire brain was reduced in our sample of recovered alcoholics.

Second, alcohol’s effect on the brain is continuous across a wide range of drinking behavior and appears to be dose specific.

Pathology is often thought of as occurring as an all-or-none phenomenon — you either have brain damage or you don’t.

This study shows that the damage occurs in gradations, and the more you drink, the greater the damage.”

Dr Fortier concluded:

“A widespread reduction in cortical tissue in recovered alcoholics indicates that even with abstinence, cognitive abilities are compromised in former drinkers.

Severe reductions in frontal brain regions can result in a dramatic change to personality and behavior, taking the form of impulsivity, difficulty with self-monitoring, planning, reasoning, poor attention span, inability to alter behavior, a lack of awareness of inappropriate behavior, mood changes, even aggression.

Severe reductions in temporal brain regions most often result in impairments in memory and language function.”

The study was published in the journal Alcoholism: Clinical & Experimental Research (Fortier et al., 2011).

Alcohol kills brain stem cells and without them, new brain cells cannot be produced.

Alcohol kills stem cells in the brain, research finds.

Stem cells are responsible for making new cells — known as neurogenesis — and are key to maintaining normal cognitive function.

Females are particularly vulnerable to the effects of alcohol on their brains, the study on mice found.

Chronic alcohol abuse is known to cause severe brain damage and neurodegeneration.

It was thought for a long time that the body did not produce any new brain cells after early life, but relatively recently it has been shown that neurogenesis does occur in the brain.

Professor Ping Wu, who led the study, said:

“The discovery that the adult brain produces stem cells that create new nerve cells provides a new way of approaching the problem of alcohol-related changes in the brain.

However, before the new approaches can be developed, we need to understand how alcohol impacts the brain stem cells at different stages in their growth, in different brain regions and in the brains of both males and females.”

Alcohol kills brain cells

The study on adult mice found that repeated alcohol consumption damaged many parts of their brains.

However, the areas that were most susceptible were in two regions that are responsible for the production of new brain cells.

The study used cutting-edge methods to tag brain stem cells and watch how they migrate and develop over time.

The study was published in the journal Stem Cell Reports (McGrath et al., 2017).

People who drank this were at a 20 percent lower risk of having a heart attack.

A moderate intake of alcohol helps to protect the heart by reducing stress signals to the brain, a study finds.

Moderate alcohol intake is between 1 and 14 drinks per week.

For the study, the brains of 752 people were scanned, focusing on the amygdala, a structure associated with stress and fear.

People who drank alcohol moderately were at a 20 percent lower risk of having a heart attack (or ‘major event’ as doctors like to call it now).

They were also likely to have lower activity in the amygdala.

Dr Kenechukwu Mezue, the study’s first author, explained:

“We found that stress-related activity in the brain was higher in non-drinkers when compared with people who drank moderately, while people who drank excessively (more than 14 drinks per week) had the highest level of stress-related brain activity.

The thought is that moderate amounts of alcohol may have effects on the brain that can help you relax, reduce stress levels and, perhaps through these mechanisms, lower the incidence of cardiovascular disease.”

Another study by the same research team found that exercise has a similar beneficial and protective effect on the heart.

The more exercise people did, the lower was their stress-associated brain activity.

Dr Mezue said:

“The current study suggests that moderate alcohol intake beneficially impacts the brain-heart connection.

However, alcohol has several important side effects, including an increased risk of cancer, liver damage and dependence, so other interventions with better side effect profiles that beneficially impact brain-heart pathways are needed.”

Alcohol causes brain damage

Although an interesting study, if you are trying to choose between moderate drinking and exercise to protect your heart and health, then there is no contest: exercise wins.

Here are some of the things that alcohol does to the brain:

• Alcohol is linked to brain damage and worse mental skills, even at relatively low levels.
• Binge drinking of alcohol is linked to brain damage.
• Binge drinking in adolescence is related to anxiety that may be permanent.
• Alcohol is the biggest avoidable risk factor for dementia.
• Long-term alcohol use is more damaging to the brain than long-term cannabis use.
• High alcohol intake can lead to a thinner cerebral cortex.
• Even moderate alcohol intake could reduce the brain’s ability to produce new cells by 40%.

The study was presented at the American College of Cardiology’s 70th Annual Scientific Session (Mezue et al., 2021).

How alcohol affects cognitive function, changes how you appear to others and even lowers the risk of some diseases.

1. Better cognitive function

Moderate consumption of wine is linked to higher performance on cognitive tests, research has found.

The study followed 5,033 people in Norway who were tracked for over 7 years.

Moderate consumptions was defined as drinking wine at least four times over a two-week period.

There was no link between drinking wines and spirits and improved cognitive function.

Women who did not drink wine actually had significantly lower scores on the tests.

2. You look more attractive

One or two glasses of wine can make the drinker look more attractive to others, a study finds.

Three or four glasses, though, does not make a person look more attractive than when they are sober.

This is different to the ‘beer goggles’ effect, which is well known: that alcohol makes other people look more attractive.

This is the first study to show that it works both ways, as the authors explain:

“The present study suggests that alcohol consumption increases ratings of attractiveness of the consumer by other people.

That is, in addition to perceiving others as more attractive, an alcohol consumer may also be perceived by others as more attractive, and therefore receive greater sexual interest from potential mates.”

3. Lower Alzheimer’s risk

One drink a day (or less) for women and 1-2 drinks (or less) for men reduces the risk of developing dementia, a study has found.

It works out to between 8 and 14 drinks per week.

The study is one of the largest — and longest — to look at the connection between alcohol and dementia.

Dr Kaycee Sink, one of the study’s authors, said:

“As of yet, we still have no cure for Alzheimer’s disease and other dementias, so it is important to look for things that might help people prevent the disease.

Moderate alcohol intake has been linked to lower risk of heart attacks, stroke, dementia, and death in middle-aged adults, but there is still controversy about alcohol intake in older adults.”

4. Lower risk of depression

Wine drunk in moderation can reduce the risk of developing depression, research finds.

Moderate alcohol intake can have a similar protective effect on depression as that found for heart disease.

Professor Miguel A. Martínez-González, one of the study’s authors, said:

“Lower amounts of alcohol intake might exert protection in a similar way to what has been observed for coronary heart disease.

In fact, it is believed that depression and coronary heart disease share some common disease mechanisms.”

5. Better memory for the past

For people over 60, light or moderate alcohol intake is associated with better recall of past events, according to a study.

Links were also found between increased size of the hippocampus — the area of the brain crucial to memory — and moderate alcohol consumption.

The study, published in the American Journal of Alzheimer’s Disease and Other Dementias, used data from almost 700 people who have been followed since the 1970s.

The results showed that people who drank alcohol lightly or moderately had better memories for past events, although there was no association with overall mental ability.

6. Improved spatial memory

One to three glasses of champagne each week could slow memory loss from ageing, research finds.

Scientists have found that phenolic compounds in champagne can help improve spatial memory.

The phenolic compounds come from the Pinot Noir and Pinot Meunier red grapes which are used alongside Chardonnay in the production of champagne.

The compounds affect the signals sent from the hippocampus to the cortex.

The compounds were found to slow the age-related decline in this signalling.

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