The Reason Some People Can’t Hold Their Drink

It’s true: some people really can’t hold their drink.

It’s true: some people really can’t hold their drink.

A gene has been identified which may help to explain why some people can’t hold their drink.

Most people know someone who only has to have a little alcohol to make them start acting very strangely.

The genetic mutation, which affects a receptor called serotonin 2B, has been identified by Finnish researchers.

Dr Roope Tikkanen, who led the research, said:

“The results also indicate that persons with this mutation are more impulsive by nature even when sober, and they are more likely to struggle with self-control or mood disorders.”

The serotonin 2B receptor is thought to be linked to impulsivity.

The mutation is present in around 2.2% of people.

Dr Tikkanen said:

“The impact of one gene on complex phenomena is typically minor.

But it is possible to identify the impact of such a genetic mutation in the Finnish population, as our historical isolation has led to a relatively homogenous gene pool.”

The study was published in the journal Translational Psychiatry (Tikkanen et al., 2015).

Drunk image from Shutterstock

Author: Dr Jeremy Dean

Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology. He has been writing about scientific research on PsyBlog since 2004.

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